Fetal nutritional origins of adult diseases: challenges for epidemiological research
نویسندگان
چکیده
منابع مشابه
Epidemiological challenges in studying the fetal origins of adult chronic disease.
The relatively new research field of the fetal origins of adult disease has matured greatly in the past decade. Recent systematic overviews provide strong evidence that robust inverse epidemiological associations exist between birthweight and later blood pressure/hypertension 1 and glucose intolerance/type 2 diabetes. 2 Consistent associations are also evident for the inverse associations of bi...
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Several decades of research have demonstrated that significant contributions to risk of cardiovascular disease are made by adult lifestyle factors such as smoking, high consumption of saturated fats and salt, low levels of physical activity, and obesity. The more recent assertion that the risk of hypertension and coronary heart disease in adult life may be determined by an adverse environment b...
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The fetal origins of adult disease (FOAD) hypothesis suggests that risk factors from intrauterine environmental exposures affect the fetus' development during sensitive periods, and increases the risk of specific diseases in adult life. This link was initially observed between prenatal exposures and adult coronary heart disease, but corresponding observations have later been published for a ran...
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To date, only a small number of commercial chemicals have been tested and documented as developmental neurotoxicants. Moreover, an increasing number of epidemiological, clinical and experimental studies suggest an association between toxicant or drug exposure during the perinatal period and the development of metabolic-related diseases and neurotoxicity later in life. The four speakers at this ...
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ژورنال
عنوان ژورنال: European Journal of Epidemiology
سال: 2008
ISSN: 0393-2990,1573-7284
DOI: 10.1007/s10654-008-9304-9